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Tue, 14 May 2013, 14:21 GMT

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Health News - Immune System

Doctors Are Missing Coeliac Disease, Warns Senior GP, Whose Daughter Has The Condition
"As doctors, we are missing many diagnoses of coeliac disease," warns a senior GP. Attending a parliamentary reception with policy makers to mark Coeliac Awareness Week, Dr Geraint Preest, a GP Principal in Bridgend is calling on doctors to "have a high index of suspicion when patients present with symptoms applicable to coeliac disease... (Medical News Today)

Signals Identified That Direct The Immune System To Reject A Transplanted Organ
Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ... (Medical News Today)

Experts Challenge Assumption, Describe Pathway That Leads To Organ Rejection
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation... (Medical News Today)

Better Understanding Of Cells' Development Has Implications In Study Of Inflammatory Diseases
Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells (ILCs). Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught... (Medical News Today)

Gender Differences In The Aging Immune System
Women's immune systems age more slowly than men's, suggests research in BioMed Central's open access journal Immunity & Ageing. The slower decline in a woman's immune system may contribute to women living longer than men... (Medical News Today)

Engineered Biomaterial Could Eliminate The Body's Negative Reaction To Medical Implants
It's a familiar scenario - a patient receives a medical implant and days later, the body attacks the artificial valve or device, causing complications to an already compromised system. Expensive, state-of-the-art medical devices and surgeries often are thwarted by the body's natural response to attack something in the tissue that appears foreign... (Medical News Today)

Immune Systems Of Women Remain Younger For Longer
The secret to why women live longer than men is due to their superior immune systems, according to a new study published in the journal Immunity & Ageing... (Medical News Today)

Phase III Clinical Trial Results For Rotavirus Vaccine Developed In India
The Government of India's Department of Biotechnology (DBT) and Bharat Biotech announced positive results from a Phase III clinical trial of a rotavirus vaccine developed and manufactured in India. Data from the trial, presented at the International Symposium on Rotavirus Vaccines for India -The Evidence and the Promise, showed ROTAVAC® to have an excellent safety and efficacy profile... (Medical News Today)

Dysregulated Cytokine-Producing Cells In Immune Response
Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory mediators. These events are important for fighting infections. However, sometimes this process goes unchecked, resulting in unwanted inflammation that can damage tissues and organs... (Medical News Today)

Infants Born To Vaccinated Mothers May Lose Initial Measles Immunity Sooner Than Those Born To Unvaccinated Mothers
Dutch study findings support earlier vaccination of newborns at high risk for measles A new Dutch study suggests that infants born to mothers who received the measles-mumps-rubella (MMR) vaccine lose their initial immunity to measles--acquired from their mothers--sooner than infants born to mothers who were naturally infected with measles... (Medical News Today)

New Global Surveillance Tool Detects And Monitors Public Concerns About Vaccines In Real Time And Could Help Boost Vaccine Uptake
Scientists have developed a global media surveillance system that enables them to look for, and systematically monitor, up-to-the-minute public concerns and rumours about vaccines originating from 144 countries... (Medical News Today)

Human Testing Of Anti-Cocaine Vaccine Likely Within A Year
Researchers at Weill Cornell Medical College have successfully tested their novel anti-cocaine vaccine in primates, bringing them closer to launching human clinical trials... (Medical News Today)

Potential Lyme Disease Vaccine Shows Promise
A vaccine for Lyme disease may be on its way, following a promising phase 1/2 clinical trial from investigators at the Stony Brook University School of Medicine and Brookhaven National Laboratory... (Medical News Today)

Cocaine Vaccine Close To Human Clinical Trials
A novel anti-cocaine vaccine has been successfully tested in primates, suggesting that human clinical trials are not far off, according to new research by Weill Cornell Medical College... (Medical News Today)

A New Vaccine To Protect Against Multiple Strains of H7N9 Bird Flu Virus
A vaccine that provides wider protection against multiple strains of the bird flu virus, H7N9, is currently being worked on as the outbreak in China continues to get worse. In a news conference held by the World Health Organization (WHO), they cautioned the public that the H7N9 virus, which is responsible for the present outbreak, is one of the most fatal seen in the latest years... (Medical News Today)

New Tool Can Identify Powerful HIV Antibodies, Could Speed HIV Vaccine Research
A team of NIH scientists has developed a new tool to identify broadly neutralizing antibodies (bNAbs) capable of preventing infection by the majority of HIV strains found around the globe, an advance that could help speed HIV vaccine research... (Medical News Today)

Gene Expression Profiling In Breast Cancer
Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most deadly types of breast cancer... (Medical News Today)

Identification Of Immune Cells That Suppress Genital Herpes Infections Has Implications For Vaccine Development
Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be responsible for suppressing recurring outbreaks of genital herpes... (Medical News Today)

GSK, Merck Cut Price Of HPV Vaccine In Poor Countries
A new all-time low price for human papillomavirus (HPV) vaccines will now help guarantee that millions of girls in poor countries are protected against cervical cancer. This will be made possible by the GAVI alliance (the Global Alliance for Vaccines and Immunization) - a public-private partnership that aims to save children's lives by funding vaccines in the world's 70 poorest nations... (Medical News Today)

Inflammatory Protein Links Type 1 Diabetes And Heart Disease
Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque... (Medical News Today)

Electricity May Be The Key To A Successful Vaccine Against Dust Mite Allergy
A new type of DNA vaccine technology could be enhanced with an electric charge during vaccination to help prevent dust mite allergies. The finding was published in Immunology Letters and details how a new type of DNA vaccine is effective in mice against dust mite allergies... (Medical News Today)

Engineered Spider Protein Promises Easier Anti-Venom Vaccines With Fewer Side Effects
Researchers in Brazil have engineered a new protein from the toxin of a reaper spider that could herald a new generation of anti-venom vaccines... (Medical News Today)

Endogenous Antibiotic Discovered In The Brain
Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. Until now, biologists had assumed that only certain fungi produced itaconic acid. A team working with Dr. Karsten Hiller, head of the Metabolomics Group at LCSB, and Dr... (Medical News Today)

In HIV Vaccine Trial In Thailand, Competing Antibodies May Have Limited The Protection Achieved
Continuing analysis of an HIV vaccine trial undertaken in Thailand is yielding additional information about how immune responses were triggered and why the vaccine did not protect more people... (Medical News Today)

Heroin Vaccine Blocks Relapse In Preclinical Study
Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing them from reaching the brain... (Medical News Today)

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